Table 4.
Odds ratios for association between cumulative exposure to cotton and wool dust, and lung cancer in two case-control studies in Montreal, Canada
| Exposure group | Study 1 | Study 2 | Pooled | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Population controls | Cancer controls | All controls, weighted | Males | Females | Population controls | |||||
| na | ORb(95% CI) | OR (95% CI) | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | |
| Cotton dust | ||||||||||
| Ever exposure | 66 | 1.4 (0.9-2.3) | 1.0 (0.7-1.4) | 1.2 (0.8-1.7) | 108 | 1.4 (1.0-2.0) | 131 | 1.0 (0.7-1.5) | 305 | 1.2 (1.0-1.5) |
| Substantial exposure | 30 | 1.5 (0.7-3.3) | 0.8 (0.5-1.3) | 1.0 (0.6-1.8) | 14 | 1.1 (0.5-2.5) | 5 | 1.0 (0.2-4.5) | 49 | 1.2 (0.7-2.0) |
| Wool dust | ||||||||||
| Ever exposure | 42 | 1.2 (0.7-2.3) | 0.8 (0.5-1.3) | 1.0 (0.6-1.6) | 46 | 0.9 (0.6-1.4) | 47 | 1.2 (0.7-2.0) | 135 | 1.0 (0.8-1.4) |
| Substantial exposure | 22 | 1.3 (0.6-3.0) | 0.7 (0.4-1.2) | 0.9 (0.5-1.7) | 8 | 1.5 (0.5-4.5) | 6 | 7.6 (0.5-107.9) | 36 | 1.5 (0.8-2.8) |
a n = number of exposed cases.
b OR refers to odds ratio, adjusted for: age, ethnicity (French Canadian or other), years of education (0-7, 8-12 or 13+), familial financial situation during childhood (difficult, intermediate or comfortable), proxy respondent (yes or no), cumulative smoking index, and any occupational exposure to asbestos, chromium, nickel or silica. Pooled results are additionally adjusted for study.