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. 2015 Apr 10;21:391–402.

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Copyright © 2015 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Linkage disequilibrium structure of the SNPs and haplotype blocks analyzed by Haploview 4.2 software. The D’ value of each SNP pair is expressed as a percentage and shown within the respective square (D’= 1 not shown). Higher D’ values are indicated in brighter red. A: LD plot of four SNPs of the DC-SIGN gene in 109 study subjects. The four SNPs constitute two haplotype blocks, with substantial LD among the SNPs of both blocks (block 1: D’ =0.95; block 2: D’=1.00). B: LD plot of four SNPs of the Dectin-1 gene in 109 study subjects. The four SNPs constitute a haplotype block spanning 0.2 kb of the Dectin-1 gene, and the magnitude of LD between each SNP was extremely high, with pair-wise D’ ≥0.92.