Figure 5. The HX mutation increases the interaction potential of Hox proteins with TFs in vivo: example in Ubx and AbdA.
(A–A′) Comparison between wild type and HX-mutated interactomes of Ubx. (B–B′) Comparison between wild type and HX-mutated interactomes of AbdA. The HX mutation led more frequently to stronger or new interactions than to interaction loses in these two Hox proteins. Colour code and representation are as in Figure 3. The HX mutation is indicated and highlighted in red. See also Figure 5—figure supplement 1.
Figure 5—figure supplement 1. The HX mutation increases the interaction potential of Hox proteins with TFs in vivo: example in Scr, Antp, and AbdB.
(A–A′) Comparison between wild type and HX-mutated Scr. (B–B′) Comparison between wild type and HX-mutated Antp. (C–C′) Comparison between wild type and HX-mutated AbdB. Colour code and representation are as in Figure 3. The HX mutation is indicated and highlighted in red.