Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Length of hospital stay
Systematic review	63 children with serologically confirmed dengue shock syndrome receiving intravenous fluids Data from 1 RCT	Mean days in hospital 7.3 days with methylprednisolone 6.2 days with placebo	MD 1.10 days 95% CI –1.83 days to +4.03 days		Not significant
Need for blood transfusions
Systematic review	Children with serologically confirmed dengue shock syndrome receiving intravenous fluids 2 RCTs in this analysis	Blood transfusions 11/39 (28%) with corticosteroid 12/50 (24%) with no corticosteroid/placebo	RR 1.08 95% CI 0.52 to 2.24 P = 0.84		Not significant
Complications
Systematic review	63 children with serologically confirmed dengue shock syndrome receiving intravenous fluids Data from 1 RCT	Pulmonary haemorrhage 1/32 (3%) with methylprednisolone 1/31 (3%) with placebo	RR 0.97 95% CI 0.06 to 14.82		Not significant
Systematic review	63 children with serologically confirmed dengue shock syndrome receiving intravenous fluids Data from 1 RCT	Convulsions 3/32 (9%) with methylprednisolone 0/31 (0%) with placebo	RR 6.79 95% CI 0.36 to 26.24		Not significant