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Summary of pharmacokinetic estimates for EF-24 following administration of a 10 mg/kg dose.
| Intravenous | Oral | Intraperitoneal | |
|---|---|---|---|
| Tmax, min | 2.7 | 3 | 3 |
| Cmax, nM | 2494 | 882 | 833 |
| t1/2α, min | 0.4 | 3.3 | 8.9 |
| t1/2β, min | 5.4 | -- | -- |
| t1/2z, min | 73.6 | 177 | 219 |
| AUC, nM•min | 59730 | 35914 | 20734 |
| C1p, L/min/kg | 0.482 | ||
| Vss, L/kg | 4.85 | ||
| Bioavailability | - | 60.1% | 34.7% |
