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. Author manuscript; available in PMC: 2015 Apr 10.
Published in final edited form as: Int Rev Cell Mol Biol. 2015 Feb 7;315:1–22. doi: 10.1016/bs.ircmb.2014.12.002

Table 1.

Proposed functional grouping of Rab proteins based on Golgi ribbon phenotype

Golgi ribbon phenotype produced by Rab inactivation or activation

Inactivation (Depletion, GDP-locked/no nucleotide form or GAP overexpression) Activation (GTP-locked form or wild-type overexpression)
Class 1A Redistribution of Golgi enzymes to the ER Normal
Class 1B Fragmented Golgi ribbon Normal
Class 2 Normal Redistribution of Golgi enzymes to the ER