Table 1.
Golgi ribbon phenotype produced by Rab inactivation or activation | ||
---|---|---|
| ||
Inactivation (Depletion, GDP-locked/no nucleotide form or GAP overexpression) | Activation (GTP-locked form or wild-type overexpression) | |
Class 1A | Redistribution of Golgi enzymes to the ER | Normal |
Class 1B | Fragmented Golgi ribbon | Normal |
Class 2 | Normal | Redistribution of Golgi enzymes to the ER |