. Author manuscript; available in PMC: 2015 Apr 10.

Published in final edited form as: Birth Defects Res B Dev Reprod Toxicol. 2010 Jun;89(3):233–238. doi: 10.1002/bdrb.20251

Table 3.

Maternal weight gain and litter parameters of CD-1 mice exposed to [C₁₀mim]Cl

	Treatment and dose (mg/kg/day)
	Vehicle Control	[C₁₀mim]Cl (50)	[C₁₀mim]Cl (75)	[C₁₀mim]Cl (100)
Maternal weight gain (g ± SEM)	11.42 ± 0.74	12.11 ± 0.70	11.42 ± 0.77	12.01 ± 0.85
Maternal Morbidity/Mortality (No./% affected dams)	0	3/12.5	2/9.5	3/12.5
Fetuses/litters examined	271/23	241/21	233/19	234/21
Implantations (mean ± SEM)	12.28 ± 0.62	12.22 ± 0.60	12.80 ± 0.49	11.39 ± 0.67
Resorbed or dead fetuses (No. ± SEM)	2.17 ± 0.93	1.49 ± 0.90	2.41 ± 1.44	4.16 ± 2.01
Litters with resorbed or dead fetuses (No./%)	5/21.7	3/14.3	3/15.8	5/23.8
Malformed fetuses (% ± SEM)^a,b	0 ± 0.0	0.62 ± 0.62	0.74 ± 0.51	0.95 ± 0.66
Malformed fetuses (% affected litters)^a	0.0	5.0	10.5	10.0
Supernumerary Ribs (% ± SEM)	13.57 ± 3.91	14.70 ± 5.04	10.48 ± 3.14	9.40 ± 2.91
Rudimentary Ribs (% ± SEM)	10.38 ± 2.78	11.71 ± 3.56	11.61 ± 2.82	4.43 ± 2.23

Fetuses displaying any gross malformation.

Grand mean of litter mean percentages.