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. Author manuscript; available in PMC: 2015 Apr 10.

Published in final edited form as: Birth Defects Res B Dev Reprod Toxicol. 2010 Jun;89(3):233–238. doi: 10.1002/bdrb.20251

Table 4.

Gross malformatiosn in CD-1 mouse fetuses exposed prenatally to [C₄mim]Cl or [C₁₀mim]C1^a,b

	Treatment and Dose (mg/kg/day)
Malformation (No./%)	[C₄mim]Cl^a				[C₁₀mim]Cl				[C₁₀mim]Cl

	0	113	169	225	0	113	169	225	0	50	75	100

Fetuses	489	288	319	314	126	170	117	35	273	267	251	239
Examined (No.)
Bent Tail	2	3	4	3	0	0	0	0	0	0	2	0
Talipes	0	0	1	0	0	0	0	0	0	0	0	0
Hemimelia	0	0	0	2	0	0	0	0	0	0	0	0
Ablepharia	2	0	1	1	0	0	1	0	0	0	0	0
Exencephaly	0	0	1	1	0	1	1	1	0	0	0	1
Craniorachischis	0	0	0	1	0	0	0	0	0	0	0	0
Ectopia Cordis	0	0	0	0	0	1	0	0	0	0	0	0
Cleft Palate	0	0	2	0	0	0	0	0	0	0	0	0
Gastroschisis	0	0	0	0	0	0	0	0	0	0	0	1

Total (No./%)	4	3	9	8	0	2	2	1	0	0	2	2

^a

[C₄mim]Cl data previously reported in Bailey et al., 2008.

^b

No malformations seen in any [C₂mim]Cl dosage group.