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. Author manuscript; available in PMC: 2015 Apr 10.
Published in final edited form as: Alcohol Clin Exp Res. 2010 Nov;34(11):1858–1870. doi: 10.1111/j.1530-0277.2010.01274.x

Table 1.

Cytokine Levels (Mean ± SE)

GRO/KC
 GRO/KC
 IFN-γ
 IFN-γ
 TNF-α
 TNF-α
 IL-1β
 IL-1β
EtOH Con LOD EtOH Con LOD EtOH Con LOD EtOH Con LOD
Serum baseline 15.74 ± 6.40 24.26 ± 13.98 22.00 0.48 ± 0.30 0.09 ± 0.07 2.96 0.45 ± 0.30 0.15 ± 0.15 37.90 1.28 ± 0.84 0.22 ± 0.22 35.20
Serum binge 90.89 ± 18.85 56.26 ± 7.06 22.00 0.28 ± 0.20 0.65 ± 0.25 2.96 0.17 ± 0.17 0 37.90 16.08 ± 5.95 7.20 ± 4.32 35.20
Serum euth 4 hour 13.35 ± 8.56 30.30 ± 14.94 30.20 1.02 ± 0.89 0 5.18 0 0 57.90 2.03 ± 2.03 0 68.10
Serum euth 24 hour 23.13 ± 12.45 50.03 ± 10.87 30.20 0.41 ± 0.35 0.57 ± 0.50 5.18 0 0 57.90 0.57 ± 0.57 2.72 ± 2.72 68.10
Liver 6.00 ± 1.06 4.48 ± 1.36 30.20 0.136 ± 0.038 0.23 ± 0.05 5.18 0.16 ± 0.10 0.02 ± 0.02 57.90 4.51 ± 0.77 6.42 ± 1.09 68.10
Brain_AV 4.98 ± 1.41 2.84 ± 0.68 27.60 1.76 ± 0.41 2.29 ± 0.47 24.00 0.70 ± 0.33 0.11 ± 0.09 51.40 7.00 ± 3.67 6.88 ± 4.09 496.00
Brain_CC 80.79 ± 55.32 11.33 ± 6.76 27.60 2.60 ± 1.10 7.031 ± 1.71 24.00 2.42 ± 1.41 5.76 ± 2.60 51.40 53.43 ± 23.50 19.24 ± 8.75 496.00
Brain_FC 34.59 ± 24.90 7.19 ± 1.76 48.60 1.90 ± 0.46 2.70 ± 1.25 39.70 3.96 ± 1.58 1.84 ± 1.24 61.60 21.31 ± 5.28 23.18 ± 10.66 165.00
Brain_Hip 27.53 ± 8.60 9.09 ± 1.37 48.60 1.28 ± 0.87 0 39.70 6.24 ± 4.13 2.29 ± 1.58 61.60 43.51 ± 16.44 26.36 ± 7.48 165.00
Brain_Hyp 104.60 ± 74.66 22.71 ± 4.39 23.30 0.45 ± 0.33 0.93 ± 0.62 10.30 15.64 ± 7.00 6.74 ± 2.91 7.40 89.19 ± 30.20 73.10 ± 25.82 339.00
Brain_Str 14.00 ± 4.14 6.93 ± 0.59 23.30 1.22 ± 0.81 1.95 ± 0.47 10.30 3.93 ± 0.35 2.31 ± 0.86 7.40 38.28 ± 22.75 27.79 ± 6.78 339.00
IL-4
 IL-4
 IL-5
 IL-5
 IL-13
 IL-13
EtOH Con LOD EtOH Con LOD EtOH Con LOD
Serum baseline 0 0 1.71 0.38 ± 0.38 0 46.80 3.41 ± 3.31 3.56 ± 3.56 1.35
Serum binge 0 0 1.71 7.07 ± 3.85 0 46.80 2.08 ± 2.08 5.62 ± 5.62 1.35
Serum euth 4 hour 0.06 ± 0.06 0 2.42 0 0 60.90 4.97 ± 3.90 11.35 ± 11.35 1.53
Serum euth 24 hour 0.45 ± 0.40 0.44 ± 0.26 2.42 0 4.5 ± 3.3 60.90 0 0 1.53
Liver 0.03 ± 0.01 0.03 ± 0.01 2.42 0.47 ± 0.12 0.63 ± 0.23 60.90 0.03 ± 0.01 0.03 ± 0.01 1.53
Brain_AV 0.14 ± 0.08 0.06 ± 0.03 4.14 2.12 ± 0.79 0.79 ± 0.60 78.30 0.56 ± 0.23 0.47 ± 0.19 10.20
Brain_CC 0.75 ± 0.53 0.45 ± 0.25 4.14 10.65 ± 7.96 3.22 ± 1.86 78.30 6.26 ± 1.69 6.17 ± 1.73 10.20
Brain_FC 0.16 ± 0.13 0.13 ± 0.06 4.38 3.59 ± 1.51 3.38 ± 2.18 78.90 0.61 ± 0.35 1.63 ± 0.90 9.82
Brain_Hip 0.05 ± 0.03 0 4.38 3.50 ± 3.04 0.55 ± 0.36 78.90 1.38 ± 0.95 0.24 ± 0.24 9.82
Brain_Hyp 0.40 ± 0.28 0 10.10 8.70 ± 7.59 1.24 ± 0.92 156.00 0.91 ± 0.58 0.23 ± 0.23 10.50
Brain_Str 0 0.06 ± 0.04 10.10 0.73 ± 0.73 1.99 ± 1.13 156.00 0.69 ± 0.68 0.51 ± 0.16 10.50

LOD, limit of detectability; EtOH n = 10, Con n = 8; except for euthanasia groups (EtOH n = 5, Con n = 4); for serum units, pg/ml; for tissue units, pg/mg protein; numbers in bold indicate levels above the LOD.