Table 3. Change in antibody response following treatment.
| At baseline | < 3 MONTHS | 3–6 MONTHS | 7–9 MONTHS | 10–18 MONTHS | > 18 MONTHS | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ELISA† | Luminex† | ELISA | Luminex | ELISA | Luminex | ELISA | Luminex | ELISA | Luminex | ELISA | Luminex | |
| No. tested | 48 | 25 | 2 | 1 | 26 | 11 | 21 | 12 | 22 | 12 | 9 | 7 |
| Range | 0–255 | 11–20321 | 0.5–9.7 | 480 | 0–89 | 3–9483 | 0.5–77 | 8–7447 | 0–33.3 | 15–6440 | 0–16.5 | 20–3324 |
| Mean | 28.8 | 3247 | 5.1 | 480 | 14.4 | 1663 | 16.3 | 1622 | 7.5 | 1293.3 | 3.7 | 1118 |
| Median | 13.8 | 596 | 5.1 | 480 | 5.9 | 448 | 4.6 | 241 | 3.5 | 168 | 1.8 | 81 |
| Ratio < 0.6 (%) * | 50 | 0 | 70 | 82 | 68 | 73 | 88 | 83 | 71 | 71 | ||
| Ratio Range | 0.3–2.3 | 0.7–0.7 | 0.1–1.4 | 0.2–0.9 | 0.1–2.2 | 0.1–0.8 | 0–3.3 | 0.1–1.4 | 0–2.4 | 0.1–2.3 | ||
Note:
† For SS-NIE-1 ELISA, units are expressed in ng/mL and for SS-NIE-1 Luminex, the unit is a ratio of mean fluorescent intensity minus the background of the test/control.
*Follow-up serologic result divided by the initial result