Table 1. A summary of the changes in D1R, D2R and Gα(olf) expression at P60.
P60 D1R | P60 D2R | P60 Gα(olf) | |||||||
---|---|---|---|---|---|---|---|---|---|
FC | CP | vMB | FC | CP | vMB | FC | CP | vMB | |
KO | – | ↓ | ↓ | ↓ | ↓ | ↓ | ↓ | – | ↓ |
KI | – | ↓ | – | ↓ | – | – | – | – | – |
hWT | – | – | – | – | – | – | N/A | N/A | N/A |
hMT | – | – | – | – | – | – | N/A | N/A | N/A |
A summary of the changes in D1R, D2R and Gα(olf) expression at postnatal day 60 (P60) in the frontal cortex (FC), caudate-putamen (CP) and ventral midbrain (vMB) in the Dyt1 KO (KO), Dyt1 KI (KI), human wild-type torsinA (hWT) and human mutant torsinA (hMT) lines of mouse.
↓ indicates statistically significant reductions in expression compared to wild-type control mice.
—indicates no statistically significant difference.
N/A differences were not analyzed.