Table 3. Evaluation of potential risk factors for overall survival after diagnosis of extra-CNS metastases (OSM+) using Kaplan Meier method and log rank test.
| subgroup | n | Deaths | Median OSM+ (months) | SE | 95% CI | p |
|---|---|---|---|---|---|---|
| male | 30 | 28 | 6.0 | 0.9 | 4.2–7.8 | 0.935 |
| female | 12 | 12 | 5.0 | 2.6 | 0.0–10.1 | |
| ≤ 42 years at ID | 22 | 21 | 5.0 | 0.8 | 3.5–6.5 | 0.686 |
| > 42 years at ID | 20 | 19 | 6.0 | 1.7 | 2.7–9.3 | |
| < 18 years at ID | 4 | 4 | 1.3 | 2.0 | 0.0–5.1 | 0.048 |
| ≥ 18 years at ID | 38 | 36 | 6.0 | 0.8 | 4.5–7.5 | |
| GBM | 37 | 35 | 6.0 | 0.7 | 4.5–7.5 | 0.264 |
| GS | 5 | 5 | 1.5 | 0.5 | 0.4–2.6 | |
| time between ID and DoM ≤ 9 months | 16 | 15 | 4.0 | 1.3 | 1.4–6.6 | 0.866 |
| time between ID and DoM > 9 months | 15 | 15 | 7.0 | 1.3 | 4.5–9.5 | |
| pulmonary involvement at DoM | 5 | 5 | 1.5 | 1.5 | 0.0–4.5 | 0.156 |
| no pulmonary involvement at DoM | 37 | 35 | 6.0 | 0.7 | 4.5–7.5 |
n: number of patients, OSM+: overall survival after the diagnosis of metastasis, SE: standard error (months), p: p-value, log-rank test, CI: confidence interval (months), ID: initial diagnosis, GBM: glioblastoma multiforme, GS: gliosarcoma, DoM: diagnosis of metastasis.