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. 2015 Mar 5;3(3):e12303. doi: 10.14814/phy2.12303

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© 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Changes in unstimulated, peak, and plateau tetanic [Ca²⁺]i during fatigue between wild-type fibers exposed to 10 μmol/L glibenclamide and 1 μmol/L verapamil. Fibers were separated into two groups: (A) fibers for which plateau tetanic [Ca²⁺]i increased during the first 10 sec (n = 8); (B) fibers for which plateau tetanic [Ca²⁺]i started to decreased immediately (n = 7). See Figure8 for a better resolution in unstimulated [Ca²⁺]i between fiber groups. ^§Mean peak (solid line) or plateau (dashed line) tetanic [Ca²⁺]i was significantly different from the prefatigue mean value (Time 0 sec). *Mean peak or plateau tetanic [Ca²⁺]i was significantly different from the mean of the fibers in A, ANOVA, and L.S.D. P < 0.05.