Table 1.
Clinical characteristics of the 26 subjects
| Mean | Range | |
|---|---|---|
| Age (years) | 49.5 ± 13.3 | 22–70 |
| Healthy subjects/subjects with mild proteinuria | 14/12 | |
| Gender (male/female) | 13/13 | |
| Body mass index (kg/m2) | 24.6 ± 4.8 | 18.7–36.0 |
| Mean blood pressure (mmHg) | 94 ± 10 | 73–114 |
| Systolic pressure (mmHg) | 127 ± 16 | 98–160 |
| Diastolic pressure (mmHg) | 78 ± 11 | 60–98 |
| Plasma glucose (mg/dL) | 91 ± 11 | 73–128 |
| Hemoglobin A1c (%) | 5.4 ± 0.4 | 4.6–6.3 |
| Inulin clearance (mL/min/1.73 m2) | 94.9 ± 23.8 | 60.2–153.3 |
| Renal plasma flow (mL/min) | 496.8 ± 171.8 | 291–873 |
| Renal blood flow (mL/min) | 810.4 ± 278.6 | 473–1451 |
| Estimated preglomerular resistance (dyne/sec/cm5) | 3778 ± 2856 | 29–9473 |
| Estimated postglomerular resistance (dyne/sec/cm5) | 1596 ± 1195 | 153–4053 |
| Filtration fraction | 0.20 ± 0.06 | 0.08–0.30 |
| Glomerular hydrostatic pressure (mmHg) | 52.0 ± 8.1 | 38.8–68.1 |
| ARB/ACEI/CCB (only in subjects in mild proteinuria) | 6/2/2 |
ARB: angiotensin receptor blocker, ACEI; angiotensin-converting enzyme, CCB; calcium channel blocker.