Table 1.
The effect of ringer or bicuculline injection into LHb and adjacent areas on physiological parameters.
Ringer | Bicuculline | ||||
---|---|---|---|---|---|
LHb (9) | LHb (9) nonparalysis | LHb (7) paralysis | Lateral (6) | 3rd ventricle (4) | |
Tail flow (%) | |||||
Before | 100 | 100 | 100 | 100 | 100 |
After | 103 ± 6 | 17 ± 4*†† | 12 ± 4**†† | 98 ± 9 | 77 ± 16 |
Pulse | |||||
Before | 100 | 100 | 100 | 100 | 100 |
After | 99 ± 1 | 11 ± 3*†† | 8 ± 3**†† | 95 ± 7 | 74 ± 18 |
Mes flow (%) | |||||
Before | 100 | 100 | 100 | 100 | 100 |
After | 99 ± 1 | 71 ± 8* | 83 ± 9 | 106 ± 5 | 101 ± 2 |
Pulse | |||||
Before | 100 | 100 | 100 | 100 | 100 |
After | 102 ± 3 | 85 ± 7 | 73 ± 6** | 92 ± 2 | 117 ± 5 |
BAT (°C) | |||||
Before | 37.4 ± 0.2 | 37.3 ± 0.2 | 37.6 ± 0.2 | 37.7 ± 0.2 | 38.1 ± 0.2 |
After | 37.3 ± 0.3 | 37.9 ± 0.2** | 38.1 ± 0.2** | 37.6 ± 0.2 | 38.2 ± 0.2 |
Body (°C) | |||||
Before | 38.9 ± 0.2 | 38.9 ± 0.7 | 39.6 ± 0.6 | 39.4 ± 0.2 | 40.2 ± 0.3 |
After | 39.0 ± 0.2 | 39.4 ± 0.2** | 39.9 ± 0.2** | 39.4 ± 0.2 | 40.4 ± 4 |
AP (mmHg) | |||||
Before | 90 ± 3 | 88 ± 3 | 84 ± 5 | 84 ± 6 | 74 ± 7 |
After | 90 ± 3 | 113 ± 7* | 119 ± 8** | 88 ± 6 | 74 ± 7 |
HR (bpm) | |||||
Before | 383 ± 7 | 373 ± 6 | 385 ± 7 | 380 ± 12 | 408 ± 10 |
After | 382 ± 7 | 415 ± 15* | 403 ± 21 | 375 ± 6 | 408 ± 11 |
Value in brackets is the number of rats. pulse, mean amplitude of pulsatory blood flow; BAT, brown adipose tissue temperature; Body, body temperature; AP, arterial pressure; HR, heart rate. *P < 0.05, **P < 0.01, significant different from mean values during 5 min before injection (before). ††P < 0.01 significant different from the corresponding value from mesenteric artery (Mes).