Table 2.
Potency of 5-HT with or without inhibition of Rho-kinase by Y-27632 in thoracic aorta of WT or SMG4 mice treated with angiotensin II (AngII)
E max_5-HT | ||
---|---|---|
WT-AngII | SMG4-AngII | |
Control | 162.3 ± 8.27 | 122.4 ± 3.38 |
1 µmol/L Y-27632 | 94.78 ± 5.17 | 75.56 ± 3.73 |
10 µmol/L Y-27632 | 42.32 ± 1.42 | 33.66 ± 1.71 |
Values are mean ± SE; n ≥ 15.