Figure 7.

Effects of genotype and diet (high- or low-fat) on hyaluronic acid level in saliva. The animals were fed either high- (HF) or low-fat (LF) diet for 2 days and then saliva samples were collected from subcongenic (n = 10) and wild-type (n = 10) mice. Bar diagrams depict means and standard errors. (A) On HF or LF diet, subcongenic and wild-type mice consumed equivalent amounts of kcal. (B) LF-fed, subcongenic mice had lower HA levels (P < 0.05, vs. wild-type controls). (C, D) Re-plotted data from A and B to facilitate comparison by diet. Both subcongenic and wild-type mice ate more HF diet (P < 0.0001, vs. LF diet) (C). (D) Subcongenic mice fed HF diet had higher HA levels (†P = 0.019, vs. LF, uncorrected t-test).