Table 1. Detailed morphological parameters for WT and Gdap1^-/- mitochondria in mouse motorneuron primary culture.

		Mean (SEM)	P value
Number of mitochondria in 100 μm
	WT	76 (6)	0.330
	Gdap1 -/-	69 (4)
Surface Area, μm2
	WT	0.16 (0.01)	0.496
	Gdap1 -/-	0.16 (0.01)
Perimeter, μm
	WT	1.60 (0.04)	0.180
	Gdap1 -/-	1.66 (0.03)
Feret's Diameter, μm
	WT	0.58 (0.01)	0.230
	Gdap1 -/-	0.61 (0.01)
Circularity (0–1)
	WT	0.77 (0.01)	0.005
	Gdap1 -/-	0.73 (0.01)**
Roundness (0–1)
	WT	0.65 (0.01)	0.120
	Gdap1 -/-	0.61 (0.02)
Aspect Ratio
	WT	1.67 (0.04)	0.011
	Gdap1 -/-	1.88 (0.07)*

Mitochondrial shape descriptors were measured in 20 WT and 30 Gdap1 ^-/- motorneurons. Student’s t test was performed for normal distributed parameters (number of mitochondria, circularity, roundness and aspect ratio) and Mann-Whitney U test for those that were non-normal distributed (surface area, Feret´s diameter and perimeter). See Fig 6 for a visual representation.

*p<0.05,

**p<0.01.