Table 2. Clinical and functional comparison between the SMA type II and III groups.
| SMA II | SMA III | |||
|---|---|---|---|---|
| N | Median [Min-Max] | N | Median [Min-Max] | |
| Age (years) | 16 | 15.4 [10.7–31.0] | 7 | 19.9 [8.3–29.9] |
| Weight * (kg) | 15 | 37.3 [21.7–52.0] | 7 | 52 [27–117] |
| Height * (cm) | 14 | 148 [130–161] | 7 | 163 [121–179] |
| Time spent in wheelchair * (months) | 16 | 184 [129–372] | 6 | 116 [45–311] |
| Forced vital capacity ** (% of predicted values) | 11 | 27 [16–70] | 5 | 78 [48–100] |
| Brooke score (#) | 16 | 4 [2–6] | 7 | 3 [2–5] |
| MFM-D2 * (%) | 16 | 36.1 [2.6–75.0] | 7 | 75.0 [11.1–88.9] |
| MFM-D3 ** (%) | 16 | 73.8 [14.3–100.0] | 7 | 95.2 [76.2–100.0] |
| MFM-Total * (%) | 16 | 31.8 [4.2–50.0] | 7 | 49.0 [20.8–57.3] |
* p-value < 0.05 for group effect,
** p-value < 0.01 for group effect.