There is an error in Fig 8. The upper panel of the figure was omitted. Please see the corrected Fig 8 here.
Fig 8. Antiviral efficacy of mIFNα2-dAb fusions and PEGylated mIFNα2 following intravenous administration.

Effect of single-dose liver-targeted IFN-α on liver HBV DNA using Southern blot hybridization (upper panel) and quantitative PCR (lower panel) in HBV transgenic mice. For statistical analysis, the data were transformed to natural log for one-way analysis of variance, after which Bonferroni’s comparison analysis was performed. (*P < 0.05, **P < 0.01, ***P < 0.001 compared to vehicle control values).
Reference
- 1. Rycroft D, Sosabowski J, Coulstock E, Davies M, Morrey J, Friel S, et al. (2015) Pharmacokinetic Characteristics, Pharmacodynamic Effect and In Vivo Antiviral Efficacy of Liver-Targeted Interferon Alpha. PLoS ONE 10(2): e0117847 doi: 10.1371/journal.pone.0117847 [DOI] [PMC free article] [PubMed] [Google Scholar]
