Table 5. Univariate and multivariate analysis for lymph node metastases and deep stromal infiltration.
Lymph node metastases | Univariate | Multivariate | >1/3 stromal infiltration | Univariate | Multivariate | |||||
---|---|---|---|---|---|---|---|---|---|---|
Variable | Negative | Positive | P | P | No | Yes | P | P | ||
Age(years) | ||||||||||
≤35 | 19 | 4 | 1.000 a | 12 | 11 | 0.514 | ||||
>35 | 215 | 47 | 155 | 107 | ||||||
FIGO stage | ||||||||||
IB1-IIA | 115 | 20 | 0.198 | 79 | 56 | 0.980 | ||||
IIB-IIIB | 119 | 31 | 88 | 62 | ||||||
Turmor size | ||||||||||
<4 | 68 | 14 | 0.77 | 54 | 28 | 0.085 | ||||
≥4 | 158 | 36 | 106 | 88 | ||||||
Grade | ||||||||||
Good or moderate | 133 | 26 | 0.414 | 92 | 67 | 0.009 | 0.027 | |||
Poor | 53 | 14 | 26 | 41 | ||||||
NACT cycles | ||||||||||
1 | 129 | 24 | 0.309 | 91 | 62 | 0.786 | ||||
2 | 106 | 27 | 77 | 56 | ||||||
Pretreatment SCC-Ag level | ||||||||||
≤3.5 | 116 | 8 | <0.001 | <0.001 | 79 | 45 | 0.041 | |||
>3.5 | 62 | 29 | 48 | 48 | ||||||
Posttreatment SCC-Ag level | ||||||||||
≤3.5 | 178 | 29 | <0.001 | 125 | 82 | 0.006 | ||||
>3.5 | 19 | 13 | 11 | 21 |
FIGO, International Federation of Gynecology and Obstetrics; NACT, neoadjuvant chemotherapy; SCC-Ag, squamous cell carcinoma antigen.
a P value calculated using fisher's exact test.