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. 2015 Apr 10;10(4):e0122361. doi: 10.1371/journal.pone.0122361

Table 5. Univariate and multivariate analysis for lymph node metastases and deep stromal infiltration.

Lymph node metastases Univariate Multivariate >1/3 stromal infiltration Univariate Multivariate
Variable Negative Positive P P No Yes P P
Age(years)
    ≤35 19 4 1.000 a 12 11 0.514
    >35 215 47 155 107
FIGO stage
    IB1-IIA 115 20 0.198 79 56 0.980
    IIB-IIIB 119 31 88 62
Turmor size
    <4 68 14 0.77 54 28 0.085
    ≥4 158 36 106 88
Grade
    Good or moderate 133 26 0.414 92 67 0.009 0.027
    Poor 53 14 26 41
NACT cycles
    1 129 24 0.309 91 62 0.786
    2 106 27 77 56
Pretreatment SCC-Ag level
    ≤3.5 116 8 <0.001 <0.001 79 45 0.041
    >3.5 62 29 48 48
Posttreatment SCC-Ag level
    ≤3.5 178 29 <0.001 125 82 0.006
    >3.5 19 13 11 21

FIGO, International Federation of Gynecology and Obstetrics; NACT, neoadjuvant chemotherapy; SCC-Ag, squamous cell carcinoma antigen.

a P value calculated using fisher's exact test.