Table 4. Liver cirrhosis status, virus status, and FGFR4 genotypic frequencies in 289 patients with HCC.
| Variable | FGFR4 rs1966265 | FGFR4 rs351855 | FGFR4 rs2011077 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| GG (N = 65) | GA+AA (N = 224) | p value | Gly/Gly (N = 82) | Gly/Arg + Arg/Arg (N = 207) | p value | GG (N = 66) | GA+AA (N = 223) | p value | |
| Child-Pugh grade | |||||||||
| A | 50 (76.9%) | 172 (76.8%) | 0.982 | 59 (72.0%) | 163 (78.7%) | 0.217 | 51 (77.3%) | 171 (76.7%) | 0.920 |
| B or C | 15 (23.1%) | 52 (23.2%) | 23 (28.0%) | 44 (21.3%) | 15 (22.7%) | 52 (23.3%) | |||
| HBsAg | |||||||||
| Negative | 32 (49.2%) | 139 (62.1%) | 0.064 | 51 (62.2%) | 120 (58.0%) | 0.510 | 33 (50.0%) | 138 (61.9%) | 0.084 |
| Positive | 33 (50.8%) | 85 (37.9%) | 31 (37.8%) | 87 (42.0%) | 33 (50.0%) | 85 (38.1%) | |||
| Anti-HCV | |||||||||
| Negative | 32 (49.2%) | 115 (51.3%) | 0.765 | 46 (56.1%) | 101 (48.8%) | 0.263 | 33 (50.0%) | 114 (51.1%) | 0.873 |
| Positive | 33 (50.8%) | 109 (48.7%) | 36 (43.9%) | 106 (51.2%) | 33 (50.0%) | 109 (48.9%) | |||
| Liver cirrhosis | |||||||||
| Negative | 16 (24.6%) | 47 (21.0%) | 0.532 | 26 (31.7%) | 37 (17.9%) | 0.010* | 16 (24.2%) | 47 (21.1%) | 0.584 |
| Positive | 49 (75.4%) | 177 (79.0%) | 56 (68.3%) | 170 (82.1%) | 50 (75.8%) | 176 (78.9%) | |||