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. 2015 Apr 10;10(4):e0123283. doi: 10.1371/journal.pone.0123283

Table 3. Predictors of being prescribed an antimalarial when the diagnostic test result for malaria was negative among infants tested in Ugandan Primary Health centers.

Patient with a negative test result for malaria Univariate analysis Multivariate Analysis
Variable Total (N = 4,972) %Prescribed an antimalarial (N = 1,545) cOR (95% CI) P Value aOR (95% CI) P Value
Age group
 1–6 days 126 34.1% 0.81 (0.55, 1.19) 0.29 *0.47 (0.32, 0.69) <0.0001
 7–31 days 338 28.7% 0.62 (0.48, 0.82) 0.001 *0.38 (0.18, 0.79) 0.01
 1–2 months 565 22.5% 0.45 (0.36, 0.57) <0.0001 *0.38 (0.25, 0.56) <0.0001
 2–3 months 776 24.5% 0.51 (0.42, 0.62) <0.0001 *0.48 (0.34,0.68) <0.0001
 3–4 months 914 27.9% 0.61 (0.50, 0.73) <0.0001 *0.60 (0.50, 0.73) <0.0001
 4–5 months 1,109 34.9% 0.84 (0.71, 0.99) 0.04 *0.82 (0.69, 0.97) 0.02
 5–6 months 1,144 39.0% ref Ref ref Ref
Fever 4,018 31.6% 1.85 (1.38, 2.49) <0.0001 *2.22 (1.47, 3.34) <0.0001
Cough or cold diagnosis 1,657 20.9% 0.47 (0.41, 0.53) <0.0001 *0.39 (0.29, 0.51) <0.0001
Diarrhea diagnosis 702 25.5% 0.73 (0.61, 0.87) 0.001 *0.62 (0.43, 0.89) 0.01
Pneumonia diagnosis 634 22.4% 0.60 (0.49, 0.73) <0.0001 *0.35 (0.25, 0.48) <0.0001
UTI diagnosis 259 5.8% 0.13 (0.08, 0.22) <0.0001 *0.16 (0.07, 0.35) <0.0001
Anemia diagnosis 33 63.6% 3.92 (1.92, 7.99) <0.0001 *3.51 (1.42, 8.70) 0.01
Return visit 56 48.2% 2.12 (1.25, 3.60) 0.01 1.55 (0.74, 3.23) 0.24
Health provider
 Medical officer 94 20.2% ref Ref ref Ref
 Clinical officer 2,506 28.5% 1.56 (0.94, 2.61) 0.08 2.01 (0.97, 4.15) 0.06
 Nurse 1,130 28.5% 1.57 (0.94, 2.65) 0.09 2.13 (0.99, 4.58) 0.05
 Midwife 32 40.6% 2.70 (1.14, 6.43) 0.03 *3.58 (1.08, 11.8) 0.04
 Other (less skilled) 581 43.2% 3.00 (1.77, 5.10) <0.0001 *4.75 (2.01, 11.2) <0.0001
EIR area
 Very high 3,166 28.4% ref ref ref ref
 Medium-high 1,267 40.3% 1.70 (1.49, 1.95) <0.0001 *2.20 (1.48 3.25) <0.0001
 Low EIR 313 31.6% 1.16 (0.91, 1.50) 0.23 1.34 (0.29, 6.01) 0.71
 Very low 226 15.5% 0.46 (0.32, 0.67) <0.0001 0.43 (0.16, 1.20) 0.11
Clinically active staff quartile
 Lowest 1,063 22.9% ref ref ref Ref
 2nd quartile 1,370 29.6% 1.42 (1.18, 1.70) <0.0001 1.14 (0.79, 1.65) 0.48
 3rd quartile 1,448 32.0% 1.59 (1.33, 1.91) <0.0001 0.96 (0.67, 1.36) 0.80
 Highest 1,091 39.7% 2.22 (1.84, 2.68) <0.0001 1.23 (0.87, 1.74) 0.25
Hospital 864 41.3% 1.73 (1.49, 2.01) <0.0001 *3.31 (1.10, 9.96) 0.03
Private Not for Profit 729 38.0% 1.44 (1.22, 1.69) <0.0001 1.34 (0.57, 3.12) 0.51
Antimalarial shortage 754 48.4% 2.42 (2.06, 2.83) <0.0001 *1.82 (1.03, 3.21) 0.04
Antibiotic shortage 2,121 39.3% 1.92 (1.70, 2.17) <0.0001 *2.23 (1.03, 4.83) 0.042
ORS shortage 1,160 39.1% 1.59 (1.39, 1.83) <0.0001 1.36 (0.96, 1.93) 0.09

* Statistically significant at 0.05 level.