Fig 2. S100A/A9 is up regulated in a murine Salmonella model.

Levels of S100A8/A9 complexes measured in plasma (A) and liver homogenates (B) from wildtype (WT) mice orally challenged with 1x10⁵ or 1x10⁶ CFU S. Typhimurium after 0 (uninfected; UI; n = 3 per group), 2 or 5 days of infection (n = 5–8 per group). (C) S100A8/A9 complexes measured in murine whole blood 4 hours after stimulation with 1x10⁵ or 1x10⁷ heat inactivated S. Typhimurium (ATCC) diluted in RPMI to a final volume of 200 μl (n = 4). Data are expressed as box-and-whisker diagrams depicting the smallest observation, lower quartile, median, upper quartile and largest observation. * P<0.05, determined using Kruskal-Wallis testing.