Table 2.
Effect of turmeric powder supplementation on biochemical parameters of diabetic subject on metformin treatment
| Parameters | Patients on metformin treatment (n = 30) | Patients on metformin + turmeric powder treatment (n = 30) | ||||
|---|---|---|---|---|---|---|
| Baseline | 1 month | P value | Baseline | 1 month | P value | |
| Fasting plasma glucose (mg/dl) | 111 ± 24 | 102 ± 18a | 0.008 | 116 ± 23 | 95 ± 11.4*** | 0.001 |
| Post prandial glucose (mg/dl) | 203 ± 36 | 196 ± 26 | 0.058 | 208 ± 31 | 197 ± 28 | 0.104 |
| Fasting plasma insulin (µU/ml) | 23 ± 16.4 | 19 ± 13 | 0.162 | 18 ± 9.9 | 22 ± 12 | 0.475 |
| Glucose/insulin ratio | 8.4 ± 7.5 | 7.6 ± 4.8 | 0.654 | 7.7 ± 3.3 | 7.8 ± 5.3 | 0.836 |
| HOMA-IR | 6.4 ± 4 | 4.7 ± 2.2 | 0.308 | 5.1 ± 2.7 | 4 ± 2.3 | 0.295 |
| HbA1c (%) | 7.8 ± 0.5 | 7.5 ± 0.7 | 0.054 | 7.9 ± 1.3 | 7.4 ± 0.9* | 0.044 |
| Urea (mg/dl) | 20 ± 7.4 | 24 ± 3.7 | 0.167 | 21.2 ± 4.2 | 22.1 ± 4.3 | 0.656 |
| Creatinine (mg/dl) | 1 ± 0.1 | 1 ± 0.1 | 0.545 | 1 ± 0.1 | 1 ± 0.1 | 0.062 |
| AST (IU/l) | 25 ± 0.1 | 25 ± 0.13 | 0.831 | 24 ± 6.0 | 26 ± 6.4 | 0.176 |
| ALT (IU/l) | 23 ± 7.2 | 25 ± 6.0 | 0.137 | 26.6 ± 11 | 23 ± 7.0 | 0.122 |
| Total protein (g/dl) | 7.3 ± 0.3 | 7.4 ± 0.3 | 0.518 | 7.3 ± 0.9 | 7.5 ± 0.4 | 0.309 |
| Albumin (g/dl) | 4.3 ± 0.3 | 4.4 ± 0.3 | 0.088 | 4.3 ± 0.2 | 4.5 ± 0.4 | 0.264 |
Data are expressed as mean ± S.D
* P < 0.05, *** P < 0.001
aComparsion of basal versus 1 month value within group