Table 3.
Effect of turmeric powder supplementation on oxidative stress parameters of diabetic patients on metformin treatment
| Parameters | Patients on metformin treatment (n = 30) | Patients on metformin + turmeric powder treatment (n = 30) | ||||
|---|---|---|---|---|---|---|
| Baseline | 1 month | P value | Baseline | 1 month | P value | |
| Glutathione (mg/gHb) | 2.4 ± 0.8 | 2.8 ± 0.6a | 0.035 | 2.5 ± 0.64 | 3.0 ± 0.68** | 0.003 |
| GPX (U/gHb) | 17.3 ± 12 | 15 ± 5 | 0.293 | 13 ± 6.0 | 14 ± 8.4 | 0.524 |
| Catalase (K/ml) | 103 ± 37 | 93 ± 16 | 0.167 | 106 ± 29 | 98 ± 25 | 0.758 |
| Protein carbonylation (nmol/g protein) | 2.7 ± 1.0 | 2.5 ± 1.0 | 0.423 | 2.6 ± 1.0 | 2.4 ± 0.8 | 0.131 |
| MDA (µmol/l) | 0.63 ± 0.3 | 0.53 ± 0.2 | 0.67 | 0.67 ± 0.16 | 0.51 ± 0.11* | 0.029 |
| Total antioxidant status (µmol/l) | 444 ± 124 | 478 ± 133 | 0.333 | 434 ± 126 | 511 ± 70* | 0.048 |
| hsCRP (mg/dl) | 5.3 ± 2.1 | 4.8 ± 2.0 | 0.346 | 4.9 ± 2.6 | 3.4 ± 2.0* | 0.03 |
Data are expressed as mean ± S.D
* P < 0.05, ** P < 0.01
aComparsion of basal versus 1 month value within group