Table 1.
KEGG pathway | Score | P value | FDR | CTEA score | CTEA P value | CTEA FDR | |
---|---|---|---|---|---|---|---|
BMI discordant | |||||||
4977 | Vitamin digestion and absorption | −0.23 | 0.002 | 0.098 | −0.23 | 0.002 | 0.065 |
4614 | Renin-angiotensin system | −0.23 | 0.003 | 0.098 | −0.22 | 0.009 | 0.195 |
eLF group | |||||||
260 | Glycine, serine and threonine metabolism | −0.19 | <0.001 | <0.001 | −0.16 | 0.001 | 0.033 |
340 | Histidine metabolism | −0.13 | 0.002 | 0.052 | −0.12 | 0.005 | 0.065 |
4977 | Vitamin digestion and absorption | −0.19 | 0.003 | 0.052 | −0.15 | 0.020 | 0.130 |
4614 | Renin-angiotensin system | −0.22 | 0.004 | 0.052 | −0.24 | 0.001 | 0.033 |
300 | Lysine biosynthesis | −0.48 | 0.004 | 0.052 | −0.44 | 0.003 | 0.065 |
780 | Biotin metabolism | −0.61 | 0.006 | 0.056 | −0.64 | 0.009 | 0.084 |
920 | Sulfur metabolism | −0.29 | 0.006 | 0.056 | −0.29 | 0.006 | 0.065 |
591 | Linoleic acid metabolism | 0.36 | 0.001 | 0.065 | 0.49 | <0.001 | <0.001 |
830 | Retinol metabolism | −0.11 | 0.011 | 0.089 | −0.19 | 0.005 | 0.065 |
1,000 permutations were performed with no probe number cutoffs. CTEA cell-type estimate adjusted.