Table 1.
T0 | T1 | ||||
---|---|---|---|---|---|
Parents (n = 918) | Siblings (n = 1054) | Controls (n = 589) | Siblings (n = 810) | Controls (n = 462) | |
Mean age (SD) | 54.8 (6.8) | 27.8 (8.3) | 30.4a
(10.6) |
30.5 (7.9) | 34.2 (10.6)b |
Male sex | 42.6% (n = 391) | 45.6% (n = 481) | 45.7% (n = 269) | 44.3% (n = 359) | 43.8% (n = 202) |
Educationc ,d | |||||
No education/primary school | 5.4% (n = 16) |
7.4% (n = 285) | 2.7% (n = 16) |
1.6% (n = 13) |
0.2% (n = 1) |
Lower (secondary/vocational) education | 47% (n = 432) | 41.4% (n = 438) | 30.2% (n = 178) | 39% (n = 316) | 28.4% (n = 131) |
Higher vocational education | 6.6% (n = 61) | 19.8% (n = 209) | 31.6% (n = 186) | 16.3% (n = 132) | 19.7% (n = 91) |
Higher (secondary) education | 34.7% (n = 319) | 29.3% (n = 309) | 35.1% (n = 207) | 42.6% (n = 345) | 51.5% (n = 238) |
Unknown | 6.2% (n = 57) |
2.2% (n = 23) |
0.3% (n = 2)a |
0.5% (n = 4) |
0.2% (n = 1)b |
Ethnic groupd | |||||
White | 88.3% (n = 811) | 83.% (n = 877) | 90.0% (n = 530) | 86.8% (n = 703) | 91.1% (n = 421) |
Other | 11.8% (n = 108) | 17% (n = 180) | 10.0% (n = 59)a | 13.2% (n = 107) | 8.9% (n = 41)b |
Diagnosise | |||||
Schizophrenia | 0% (n = 0) | 0% (n = 0) |
0% (n = 0) | 0.7% (n = 6) | 0% (n = 0) |
Other psychosis | 0% (n = 0) | 0% (n = 0) |
0% (n = 0) | 0.3 (n = 2) | 0% (n = 0) |
Mood disorders | 18.8% (n = 173) | 11.7% (n = 124) | 8.7% (n = 51) | 17.5% (n = 142) | 13% (n = 60) |
Substance abuse/dependence | 0.1% (n = 1) | 0.3% (n = 3) | 0% (n = 0) | 0.1% (n = 1) | 0.2% (n = 1) |
Anxiety disorders | 0.5% (n = 5) | 0% (n = 0) |
0.2% (n = 1) | 0.6% (n = 5) | 0.4% (n = 2) |
Personality disorders | 0% (n = 0) | 0.2% (n = 2) | 0% (n = 0) | 0.1% (n = 1) | 0% (n = 0) |
Other diagnosis | 0.1% (n = 1) | 0.7% (n = 7) | 0.3% (n = 2) | 1% (n = 8) | 0.2% (n = 1) |
Postponed diagnosis | 0.1 (n = 1) | 0.5% (n = 5) | 0.5% (n = 3) | 0.3% (n = 2) | 0.9% (n = 4) |
No diagnosis | 80.3% (n = 738) | 86.7% (n = 916) | 89.8 (n = 532) | 79.4% (n = 643) | 84.9% (n = 392) |
Missing | 0 | 0 | 0 | 0 | 0% (n = 0) |
Notes: aControl group differs from healthy siblings OAF group at T0 (p < .05).
bControl group differs from healthy siblings OAF group at T1 (p < .05).
cEducation: no/primary: no or only primary school, lower secondary education: LBO/HH/LHNO/VBO, MAVO/VMBO, higher vocational education: MBO, higher secondary education: HAVO, VW0, HBO, and University.
dT0 sample differs significantly from T1 sample (p <.05).
eOther diagnoses include cognitive disorder, developmental disorder, anorexia, and adjustment disorder.