. 2014 Dec 20;41(3):637–643. doi: 10.1093/schbul/sbu172

Table 2.

Mean C-RDPSS Scores and Adjusted Standardized Mean Difference (Hedge’s g) in C-RDPSS Scores Between Placebo and Active Treatment at Baseline and at Week 6

	Hallucinations	Delusions	Disorganized speech	Abnormal psychomotor behavior	Negative symptoms	Impaired cognition	Depression	Mania
Placebo (N = 1506)
Mean (SD)
Baseline	2.56 (1.12)	3.07 (0.63)	2.51 (0.99)	1.90 (1.07)	2.64 (0.84)	0.93 (1.08)	1.64 (1.20)	1.98 (1.16)
6 weeks	2.15 (1.36)	2.68 (1.05)	2.24 (1.25)	1.71 (1.17)	2.40 (1.04)	0.91 (1.14)	1.33 (1.23)	1.83 (1.30)
P	<.001	<.001	<.001	<.001	<.001	.75	<.001	.04
Active (N = 3727)
Mean (SD)
Baseline	2.58 (1.10)	3.04 (0.65)	2.48 (1.01)	1.90 (1.09)	2.66 (0.82)	0.97 (1.08)	1.65 (1.19)	2.04 (1.14)
6 weeks	1.74 (1.34)	2.37 (1.10)	1.88 (1.19)	1.53 (1.10)	2.25 (0.99)	0.72 (0.99)	1.15 (1.14)	1.54 (1.25)
P	<.001	<.001	<.001	<.001	<.001	<.001	.15	<.001
Hedge’s g^a baseline	0.01	−0.04	−0.03	0.00	0.03	0.04	0.00	0.05
95% CI	−0.05 to 0.07	−0.1 to 0.02	−0.09 to 0.03	−0.06 to 0.06	−0.03 to 0.09	−0.02 to 0.1	−0.05 to 0.07	−0.01 to 0.11
Hedge’s g^a 6 weeks	−0.31	−0.29	−0.29	−0.17	−0.15	−0.18	−0.15	−0.23
95% CI	−0.37 to −0.25	−0.35 to −0.23	−0.35 to −0.23	−0.23 to −0.11	−0.21 to −0.09	−0.24 to −0.12	−0.21 to −0.09	−0.29 to −0.17

^aHedge’s g was calculated with the formula $(1 - \frac{3}{4 d f - 1}) \times (\frac{R_{1} - R_{2}}{S_{within}})$ where $S_{within} = \sqrt{\frac{(n_{1} - 1) s_{1}^{2} + (n_{2} - 1) s_{2}^{2}}{n_{1} + n_{2} - 2}}$ .