Table 3.
Mean C-RDPSS Scores and Adjusted Standardized Mean Difference (Hedge’s g) in C-RDPSS Scores Between Nonresponders and Responders at Baseline and at Week 6
Hallucinations | Delusions | Disorganized speech | Abnormal psychomotor behavior | Negative symptoms | Impaired cognition | Depression | Mania | |
---|---|---|---|---|---|---|---|---|
Non-responder (N = 3788) | ||||||||
Mean (SD) | ||||||||
Baseline | 2.54 (1.12) | 3.05 (0.65) | 2.52 (0.99) | 1.90 (1.07) | 2.64 (0.84) | 1.01 (1.09) | 1.60 (1.19) | 2.01 (1.15) |
6 weeks | 2.26 (1.26) | 2.85 (0.86) | 2.35 (1.10) | 1.83 (1.10) | 2.56 (0.89) | 0.96 (1.10) | 1.43 (1.19) | 1.97 (1.22) |
P | <.001 | <.001 | <.001 | .005 | .08 | .27 | <.001 | .81 |
Responder (N = 1445) | ||||||||
Mean (SD) | ||||||||
Baseline | 2.65 (1.06) | 3.06 (0.61) | 2.41 (1.03) | 1.89 (1.11) | 2.71 (0.78) | 0.84 (1.04) | 1.76 (1.21) | 2.04 (1.11) |
6 weeks | 0.80 (0.99) | 1.44 (0.99) | 1.02 (0.96) | 0.92 (0.90) | 1.59 (0.96) | 0.30 (0.63) | 0.60 (0.85) | 0.71 (0.89) |
P | <.001 | <.001 | <.001 | <.001 | <.001 | <.001 | <.001 | <.001 |
Hedge’s ga baseline | 0.09 | 0.03 | −0.10 | 0.01 | 0.08 | −0.15 | 0.13 | 0.02 |
95% CI | 0.03 to 0.16 | −0.03 to 0.09 | −0.16 to 0.04 | −0.07 to 0.05 | 0.02 to 0.14 | −0.21 to −0.09 | 0.07 to 0.19 | −0.04 to 0.08 |
Hedge’s ga 6 weeks | −1.23 | −1.56 | −1.25 | −0.87 | −1.06 | −0.66 | −0.75 | −1.11 |
95% CI | −1.30 to −1.17 | −1.63 to −1.49 | −1.31 to −1.18 | −0.93 to −0.81 | −1.12 to −1.00 | −0.72 to −0.60 | −0.81 to −0.67 | −1.17 to −1.04 |
aHedge’s g was calculated with the formula where .