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. Author manuscript; available in PMC: 2016 Apr 11.
Published in final edited form as: Toxicol Appl Pharmacol. 2014 Oct 11;281(1):67–77. doi: 10.1016/j.taap.2014.09.015

Figure 2.

Figure 2

BDE-47-stimulated ARE reporter activity in HTR-8/SVneo cells. Cells were exposed to solvent control (0.7% v/v DMSO) or BDE-47 treatment for 6 or 24 h, and then ARE reporter activity was assessed as an indicator of Nrf2 activation. Data are presented as means±SEM fold change over solvent control (dashed line) for each respective time point. To derive fold changes, firefly luciferase relative light unit (RLU) values were first normalized to Renilla luciferase to compensate for cell number and transfection efficiency, then fold changes were calculated relative to solvent control for each time point (n=3 experiments). Each experiment was performed in triplicate.*P<0.05, significant compared to solvent control within same time point.