Table 3.

Association between putative mediators and parental diabetes

Mediator	Number of parents with diabetes			p value
	None (n=1965)	One (n=370)	Two (n=26)
CIR	2.31 [1.47, 4.00]	2.30 [1.42, 4.25]	1.79 [0.96, 2.86]	0.01
HOMA-IR	6.22 [5.11, 7.86]	6.59 [5.40, 8.33]	6.41 [4.71, 7.99]	0.01
MSS	1 [1, 2]	1 [1, 3]	2 [1, 3]	0.03
Diet score	12 [10, 14]	12 [10, 14]	11 [9, 14]	0.20
Physical activity	33.2 [30.4, 36.8]	33.8 [30.7, 36.7]	33.1 [31.4, 36.7]	0.93
GRS	66.4 [63.1, 69.9]	67.6 [63.5, 71.4]	71.1 [66.1, 72.5]	0.004

Data are presented as median (interquartile range)