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. Author manuscript; available in PMC: 2015 Apr 12.
Published in final edited form as: J Am Chem Soc. 2015 Feb 19;137(8):3031–3040. doi: 10.1021/ja512605w

Figure 4.

Figure 4

Key interactions between RNA and Rho during the I → F transition. (a) Free energy landscape along distances P3-K326(m1) and P6-K326(m4). The position of the phosphorus atoms of the phosphate group and NZ atoms of K326 define the corresponding distances. (b–e) Configurations in states I, IM1, IM2 and F, accounting for the key steps of RNA binding and release that induce RNA translocation. Red dashed arrows indicate large side chain movements before the next state is reached. m1 (green) and m4 (orange) are shown in transparent surfaces.