Table 10.
Analysis of BDNF expression level depending on the clinical parameters in patients with primary open angle glaucoma (POAG) for each eye counted.
| Clinical parameter | Stage of POAG | Number of POAG | Mean (expression level − ΔCt) | SD (expression level − ΔCt) |
Quartile 25% |
Median | Quartile 75% |
P |
|---|---|---|---|---|---|---|---|---|
| Normal (0–30) |
53 | 19.43 | 1.43 | 18.47 | 19.46 | 20.43 | ||
| NFI | Early (31–50) |
13 | 19.34 | 1.03 | 18.89 | 19.50 | 19.84 | 0.681 |
| Advanced (>51) |
4 | 18.82 | 0.77 | 18.28 | 18.75 | 19.36 | ||
|
| ||||||||
| Normal (<0.3) |
0 | — | — | — | — | — | ||
| c/d | Early (0.3–0.7) |
53 | 19.56 | 1.44 | 18.60 | 19.19 | 20.71 | 0.260 |
| Advanced (>0.7) |
50 | 19.18 | 1.28 | 18.16 | 19.09 | 19.89 | ||
|
| ||||||||
| RA | Normal (1.39–1.78) |
33 | 20.33 | 1.25 | 19.06 | 19.67 | 20.65 | 0.011 |
| Early (1.26–1.38) |
9 | 19.94 | 1.52 | 18.87 | 19.50 | 21.50 | ||
| Middle-advanced (0.81–1.25) |
34 | 19.25 | 1.16 | 18.87 | 19.28 | 19.82 | ||
| Advanced (<0.81) |
9 | 18.68∧ | 1.50 | 17.76 | 18.21 | 18.91 | ||
|
| ||||||||
| RNFL | Normal (0.21–0.31) |
39 | 19.79 | 1.34 | 18.94 | 19.62 | 20.59 | 0.360 |
| Early (0.20–0.18) |
7 | 19.82 | 1.48 | 19.28 | 19.83 | 20.39 | ||
| Middle-advanced (0.13–0.17) |
18 | 19.17 | 1.05 | 18.60 | 19.26 | 19.77 | ||
| Advanced (<0.13) |
21 | 19.40 | 1.47 | 18.21 | 19.06 | 19.82 | ||
NFI: nerve fiber index; c/d: cup disc ratio; RA: rim area; RNFL: retinal nerve fiber layer.
Tukey's HSD test: P < 0.05 (∧normal versus advanced).