Table 1 .
Quintile of non-dairy dietary calcium | ||||||
---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | Q5 | P for trend | |
HPFS | ||||||
Age, y | 48.2 | 48.6 | 49.1 | 49.4 | 49.2 | <0.001 |
Body mass index, kg/m2 | 25.6 | 25.6 | 25.6 | 25.5 | 25.3 | <0.001 |
Hypertension (%) | 16.7 | 16.7 | 16.2 | 16.4 | 16.6 | 0.66 |
Thiazide use (%) | 5.8 | 6.0 | 5.4 | 6.0 | 5.3 | 0.22 |
Diabetes Mellitus (%) | 0.9 | 1.5 | 2.0 | 2.2 | 2.7 | <0.001 |
Supplemental calcium, mg/d | 56 | 70 | 79 | 99 | 134 | <0.001 |
Dairy calcium, mg/d | 475 | 491 | 474 | 464 | 432 | <0.001 |
Non-dairy dietary calcium, mg/d | 238 | 289 | 318 | 351 | 434 | <0.001 |
NHS I | ||||||
Age, y | 51.9 | 52.4 | 52.7 | 52.9 | 53.1 | <0.001 |
Body mass index, kg/m2 | 24.7 | 25.0 | 25.2 | 25.5 | 25.7 | <0.001 |
Hypertension (%) | 23.2 | 23.2 | 24.4 | 26.0 | 27.0 | <0.001 |
Thiazide use (%) | 11.0 | 11.9 | 12.5 | 13.3 | 14.9 | <0.001 |
Diabetes Mellitus (%) | 1.8 | 2.6 | 3.3 | 4.1 | 5.1 | <0.001 |
Supplemental calcium, mg/d | 307 | 336 | 360 | 381 | 413 | <0.001 |
Dairy calcium, mg/d | 437 | 452 | 448 | 437 | 414 | <0.001 |
Non-dairy dietary calcium, mg/d | 262 | 304 | 329 | 357 | 419 | <0.001 |
NHS II | ||||||
Age, y | 35.7 | 36.0 | 36.2 | 36.3 | 36.4 | <0.001 |
Body mass index, kg/m2 | 24.6 | 24.5 | 24.6 | 24.7 | 24.6 | 0.28 |
Hypertension (%) | 6.3 | 5.6 | 6.2 | 6.4 | 6.9 | 0.02 |
Thiazide use (%) | 1.3 | 1.5 | 1.8 | 2.0 | 2.0 | <0.001 |
Diabetes Mellitus (%) | 0.5 | 0.7 | 0.9 | 1.1 | 1.5 | <0.001 |
Supplemental calcium, mg/d | 103 | 113 | 124 | 137 | 165 | <0.001 |
Dairy calcium, mg/d | 617 | 609 | 584 | 555 | 513 | <0.001 |
Non-dairy dietary calcium, mg/d | 253 | 302 | 332 | 364 | 440 | <0.001 |
Mean values were derived from responses to the 1986 (HPFS and NHS I) and 1991 (NHS II) questionnaires.
Note: Nutrient values were adjusted for caloric intake. Supplemental calcium also includes calcium from multivitamin preparations.
HPFS: Health Professionals Follow-up Study
NHS: Nurses’ Health Study