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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Neuropharmacology. 2014 Oct 12;96(0 0):169–177. doi: 10.1016/j.neuropharm.2014.10.002

Figure 4. The δ-subunit four-helix bundle site.

Figure 4

The nAChR TMD structure is depicted as backbone ribbons, viewed from above. The δ subunit four-helix bundle is shown along with another perspective on the γ+/α-interfacial site. Anesthetic photolabeled residues are shown as ball-and-stick structures, colored according to which anesthetics modified them: halothane = green; azi-etomidate = gold; TID or aziPm = dark blue; azi-octanol = cyan.