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Effects of YW3-56 on gene expression in xenograft tumors.
| Treatment | PBS | YW3-56 (12.5 mg/kg) | PBS | YW3-56 (40 mg/kg) | |||
|---|---|---|---|---|---|---|---|
| Genes | 4L | 5L | 6L | 1R | 11L | ||
| SESN2 | 1 ±0.22 | 5.4 | 83.2 | 1.5 | 1 ±0.08 | 22.1 | 5.3 |
| DDIT4 | 1 ±0.03 | 19.8 | 3.9 | 1.4 | 1 ±0.22 | 1.4 | 2.2 |
| GADD45 | 1 ±0.08 | 5.0 | 5.1 | 0.7 | 1 ±0.06 | 13.2 | 1.1 |
| PUMA | 1 ±0.22 | 2.6 | 116.8 | 1.1 | 1 ±0.11 | 23.9 | 5.1 |
| DDIT3 | 1 ±0.14 | 1.8 | 63.7 | 1.9 | 1 ±0.23 | 24.2 | 2.1 |
