Figure 2.
Concentration-response curves for acetylcholine in rat hepatic arterial rings precontracted with phenylephrine in presence of L-NAME (A) and after pretreatment with L-NAME + indomethacin (B). Control (n = 12): hepatic artery rings were reoxygenated in the organ bath without cold storage and pretreated with L-NAME. IGL-1 (n = 11): hepatic artery rings were reoxygenated in the organ bath after cold preservation in IGL-1 solution and pretreatment. Celsior (n = 11): hepatic artery rings were reoxygenated in the organ bath after cold preservation in Celsior solution and pretreatment. aP < 0.05 vs Control + L-NAME, cP < 0.05 vs IGL-1 + L-NAME. IGL-1: Institut Georges Lopez-1.