Table 3.
Allele Frequencies of SNPs in IL1A and IL1B Genes in Periodontitis Patients and Controls
| SNP in IL-1 gene | Controls | Cases | OR (unadjusted) 95% CI | p-Value |
|---|---|---|---|---|
| (rs1800587) IL1A −889 C>T | ||||
| C | 293 | 287 | Ref | — |
| T | 107 | 113 | 1.08 (0.79–1.47) | 0.635 |
| (rs17561) IL1A +4845 G>T | ||||
| G | 277 | 273 | Ref | — |
| T | 123 | 127 | 1.05 (0.78–1.41) | 0.760 |
| (rs16944), IL1B −511 C>T | ||||
| C | 276 | 252 | Ref | — |
| T | 124 | 148 | 1.31 (0.97–1.75) | 0.073 |
| (rs1143634), IL1B +3954C>T | ||||
| C | 326 | 298 | Ref | — |
| T | 74 | 102 | 1.51 (1.07–2.11) | 0.017* |
*
Bold indicates p-value <0.05, statistically significant.