Table 4.
Association Analysis (CLUMP) of ILRN VNTR Polymorphism with Chronic Periodontitis
| Case (periodontitis) | Control | T1 | T2 | T3 | T4 | |
|---|---|---|---|---|---|---|
| Genotype | ||||||
| a1a1 | 137 (68.5) | 127 (63.5) | ||||
| a1a2 | 21 (10.5) | 23 (11.5) | ||||
| a2a2 | 7 (3.5) | 18 (9) | ||||
| a1a3 | 5 (2.5) | 4 (2) | ||||
| a3a3 | 7 (3.5) | 7 (3.5) | χ2 value: 7.841 | χ2 value: 5.567 | χ2value: 5.163 | χ2 value:5.163 |
| a1a4 | 13 (6.5) | 11 (5.5) | df=9 | df=4 | df=1 | df=1 |
| a2a4 | 1 (0.5) | 1 (0.5) | p=0.550 | p=0.234 | p=0.023 | p=0.468 |
| a3a4 | 3 (1.5) | 4 (2) | ||||
| a4a4 | 4 (2) | 5 (2.5) | ||||
| a1a5 | 2 (1) | 0 (0) | ||||
| HW p-value | <0.001 | <0.001 | ||||
| Alleles | ||||||
| a1 | 315 (78.8) | 292 (73.0) | ||||
| a2 | 36 (9.0) | 60 (15.0) | ||||
| a3 | 22 (5.5) | 22 (5.5) | χ2 value: 8.891 | χ2 value: 6.978 | χ2 value: 6.818 | χ2 value: 6.818 |
| a4 | 25 (6.3) | 26 (6.5) | df=4 | df=3 | df=1 | df=1 |
| a5 | 2 (0.5) | 0 (0.0) | p=0.064 | p=0.072 | p=0.009 | p=0.041 |
T1, T2, T3, and T4 are Pearson's χ2 respectively for raw, rare alleles grouped together, 2×2 tables that compare one column against the rest grouped, and 2×2 tables comparing any combination of columns against the rest. p-Value<0.05, statistically significant.