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. 2015 Apr 1;5(3):137–146. doi: 10.1089/brain.2014.0299

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Copyright 2015, Mary Ann Liebert, Inc.

PMC Copyright notice

FIG. 3. — Sample individual maps of the functional connectivity strength of the default mode network, dynamic CBF-BOLD coupling, and macrovascular volume fraction. Maps of (a) functional connectivity strength (in terms of z-statistics) and (b) CBF-BOLD coupling are both overlaid on a cortical surface model. (a) Connectivity is shown at this point for the default mode network. (b) Significantly positive CBF-BOLD coupling is detected in the main regions of networks such as default mode and frontoparietal networks. (c) Macrovascular volume fraction includes the resting blood volume fractions of both pial vessels and intracranial vessels. The regional association between the dynamic CBF-BOLD coupling and macrovascular volume fraction with functional connectivity strength was quantitatively explored using an ROI analysis.