Table 8.

GO Enrichment Analysis for the Mutation Subnetwork of AML 2.1 (Composed of 21 Common AML Mutations and Their First Neighbors, for a Total of 257 Genes)

GO term	Description	Count	p	Fold enrichment	False discovery rate
GO:0006259	DNA metabolic process	43	4.28E-16	4.47	7.55E-13
GO:0051276	Chromosome organization	42	5.06E-16	4.56	9.44E-13
GO:0006396	RNA processing	42	3.00E-14	4.04	5.08E-11
GO:0006974	Response to DNA damage stimulus	33	7.17E-13	4.66	1.22E-09
GO:0007049	Cell cycle	47	3.29E-12	3.19	5.58E-09
GO:0033554	Cellular response to stress	39	8.55E-12	3.63	1.45E-08
GO:0006281	DNA repair	27	2.79E-11	5.00	4.73E-08
GO:0016568	Chromatin modification	23	1.16E-08	4.42	1.97E-05
GO:0006260	DNA replication	18	1.20E-07	4.99	2.03E-04
GO:0016570	Histone modification	14	5.17E-07	6.04	8.77E-04
GO:0010941	Regulation of cell death	37	1.69E-06	2.39	0.0029
GO:0034621	Cellular macromolecular complex subunit organization	22	4.39E-06	3.24	0.0074
GO:0045934	Negative regulation of nucleobase, nucleoside, nucleotide, and nucleic acid metabolic process	27	4.67E-06	2.78	0.0079