Figure 4. Cell proliferation after DSB treatment.

(a) Liver sections were immunostained for Ki67 after SacI adenoviral tail-vein injection as indicated and images acquired at × 10 magnification. Scale bar, 150 μM. (b) Quantification of the per cent of Ki67+ nuclei of total nuclei from three images per n, where AdV, 1 mo, 2 mo post DSB n=4, 24 h V+D n=2 and old n=3. Data represent the mean±s.e.m. P values were determined using Student's unpaired t-test. ***P<0.001. Mo, months; wk, weeks.