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. 2015 Mar 24;112(14):4334–4339. doi: 10.1073/pnas.1503262112

Fig. 1.

Fig. 1.

The endpoint structures (1,000 ns) of the (A) glycosylated and (B) nonglycosylated EGFR in DOPC/SM/cholesterol membranes. The receptor structure is color-coded throughout the panels as follows: subdomains DI (blue), DII (green), DIII (yellow), and DIV (red); TM domain (orange); intracellular TKD (salmon); glycans (purple). (C and D) The distances of the center of mass of subdomains DI and DIII to the membrane (Upper) and membrane interface area of ECD subdomains DI–DIV (Bottom), for (C) glycosylated and (D) nonglycosylated EGFR. For corresponding PDB files, see Datasets S1–S4.