Table 3.
Biomarker | N | Age | Brushing Frequency | Days Since Professional Cleaning |
Mean Probing Depth |
Mean Plaque Index | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
PISF | GCF | PISF | GCF | PISF | GCF | PISF | GCF | PISF | GCF | |||
IL1−α | 73 | r | 0.10 | 0.03 | −0.33 | −0.36 | 0.24 | 0.10 | 0.29 | 0.34 | 0.28 | 0.40 |
p | 0.40 | 0.78 | <0.01* | <0.01* | <0.05* | 0.38 | <0.05* | <0.01* | <0.05* | <0.01** | ||
IL1−β | 73 | r | 0.13 | 0.12 | −0.30 | −0.32 | 0.33 | 0.15 | 0.39 | 0.38 | 0.22 | 0.34 |
p | 0.27 | 0.33 | <0.01* | <0.05* | <0.05* | 0.19 | <0.01** | <0.01* | 0.06 | <0.01* | ||
IL−4 | 73 | r | 0.14 | 0.07 | −0.17 | −0.15 | 0.20 | 0.19 | 0.16 | 0.24 | 0.13 | 0.27 |
p | 0.23 | 0.56 | 0.14 | 0.20 | 0.09 | 0.12 | 0.17 | <0.05* | 0.26 | <0.05* | ||
IL−6 | 73 | r | 0.18 | −0.10 | 0.05 | −0.04 | 0.09 | 0.13 | 0.29 | 0.18 | 0.08 | 0.07 |
p | 0.13 | 0.39 | 0.68 | 0.74 | 0.44 | 0.28 | <0.05* | 0.12 | 0.52 | 0.55 | ||
IL−8 | 73 | r | −0.07 | −0.21 | −0.22 | −0.20 | 0.11 | −0.04 | 0.40 | 0.08 | −0.03 | 0.04 |
p | 0.55 | 0.07 | 0.06 | 0.09 | 0.35 | 0.71 | <0.01** | 0.49 | 0.81 | 0.73 | ||
IL−10 | 73 | r | 0.24 | 0.09 | −0.20 | −0.11 | 0.32 | 0.31 | 0.30 | 0.23 | 0.15 | 0.25 |
p | <0.05* | 0.44 | 0.08 | 0.34 | <0.01* | <0.01* | <0.01* | 0.05 | 0.19 | <0.05* | ||
IL−12 | 73 | r | 0.30 | 0.32 | −0.28 | −0.19 | 0.16 | 0.23 | 0.23 | 0.23 | 0.23 | 0.47 |
p | <0.01* | <0.01* | <0.05* | 0.10 | 0.17 | <0.05* | 0.05 | <0.05* | <0.05* | <0.01** | ||
IL−17 | 73 | r | 0.14 | 0.10 | −0.17 | −0.09 | 0.24 | 0.29 | 0.16 | 0.11 | 0.17 | 0.19 |
p | 0.22 | 0.40 | 0.14 | 0.47 | <0.05* | <0.05* | 0.19 | 0.37 | 0.15 | 0.11 | ||
TNF−α | 73 | r | 0.11 | 0.03 | −0.16 | −0.15 | 0.09 | 0.06 | 0.33 | 0.18 | 0.11 | 0.23 |
p | 0.35 | 0.78 | 0.17 | 0.19 | 0.47 | 0.60 | <0.01* | 0.13 | 0.34 | 0.05 | ||
CRP | 60 | r | 0.11 | 0.02 | 0.06 | −0.04 | 0.18 | 0.03 | 0.18 | 0.11 | 0.13 | 0.01 |
p | 0.42 | 0.86 | 0.65 | 0.76 | 0.17 | 0.80 | 0.16 | 0.42 | 0.33 | 0.92 | ||
OPG | 57 | r | −0.03 | −0.01 | −0.05 | 0.06 | 0.06 | 0.04 | 0.29 | 0.19 | −0.07 | −0.05 |
p | 0.81 | 0.96 | 0.74 | 0.68 | 0.66 | 0.77 | <0.05* | 0.16 | 0.62 | 0.74 | ||
Leptin | 57 | r | 0.16 | 0.24 | −0.09 | −0.09 | 0.00 | 0.00 | 0.10 | 0.05 | 0.10 | 0.11 |
p | 0.23 | 0.07 | 0.52 | 0.51 | 0.99 | 0.98 | 0.48 | 0.73 | 0.47 | 0.43 | ||
Adiponectin | 39 | r | 0.11 | 0.03 | −0.16 | −0.09 | 0.20 | 0.09 | 0.43 | 0.08 | −0.01 | −0.03 |
p | 0.52 | 0.84 | 0.33 | 0.57 | 0.21 | 0.59 | <0.01* | 0.62 | 0.94 | 0.87 |
Spearman correlation coefficient is denoted by ‘r’ and ‘p’ refers to p−value for that correlation.
p<0.05
Significant after adjusting for multiple comparisons, i.e., unadjusted p−value < 0.0008. The significant correlations are highlighted.