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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: J Periodontol. 2014 Sep 30;86(2):264–272. doi: 10.1902/jop.2014.140354

Table 3.

Spearman rank correlations between measurements taken at the implant and at the control tooth site for each of 13 biomarkers, and the covariates age, brushing frequency, days since professional cleaning, mean probing depth and mean plaque index.

Biomarker N Age Brushing Frequency Days Since
Professional
Cleaning
Mean Probing
Depth
Mean Plaque Index
PISF GCF PISF GCF PISF GCF PISF GCF PISF GCF
IL1−α 73 r 0.10 0.03 −0.33 −0.36 0.24 0.10 0.29 0.34 0.28 0.40
p 0.40 0.78 <0.01* <0.01* <0.05* 0.38 <0.05* <0.01* <0.05* <0.01**
IL1−β 73 r 0.13 0.12 −0.30 −0.32 0.33 0.15 0.39 0.38 0.22 0.34
p 0.27 0.33 <0.01* <0.05* <0.05* 0.19 <0.01** <0.01* 0.06 <0.01*
IL−4 73 r 0.14 0.07 −0.17 −0.15 0.20 0.19 0.16 0.24 0.13 0.27
p 0.23 0.56 0.14 0.20 0.09 0.12 0.17 <0.05* 0.26 <0.05*
IL−6 73 r 0.18 −0.10 0.05 −0.04 0.09 0.13 0.29 0.18 0.08 0.07
p 0.13 0.39 0.68 0.74 0.44 0.28 <0.05* 0.12 0.52 0.55
IL−8 73 r −0.07 −0.21 −0.22 −0.20 0.11 −0.04 0.40 0.08 −0.03 0.04
p 0.55 0.07 0.06 0.09 0.35 0.71 <0.01** 0.49 0.81 0.73
IL−10 73 r 0.24 0.09 −0.20 −0.11 0.32 0.31 0.30 0.23 0.15 0.25
p <0.05* 0.44 0.08 0.34 <0.01* <0.01* <0.01* 0.05 0.19 <0.05*
IL−12 73 r 0.30 0.32 −0.28 −0.19 0.16 0.23 0.23 0.23 0.23 0.47
p <0.01* <0.01* <0.05* 0.10 0.17 <0.05* 0.05 <0.05* <0.05* <0.01**
IL−17 73 r 0.14 0.10 −0.17 −0.09 0.24 0.29 0.16 0.11 0.17 0.19
p 0.22 0.40 0.14 0.47 <0.05* <0.05* 0.19 0.37 0.15 0.11
TNF−α 73 r 0.11 0.03 −0.16 −0.15 0.09 0.06 0.33 0.18 0.11 0.23
p 0.35 0.78 0.17 0.19 0.47 0.60 <0.01* 0.13 0.34 0.05
CRP 60 r 0.11 0.02 0.06 −0.04 0.18 0.03 0.18 0.11 0.13 0.01
p 0.42 0.86 0.65 0.76 0.17 0.80 0.16 0.42 0.33 0.92
OPG 57 r −0.03 −0.01 −0.05 0.06 0.06 0.04 0.29 0.19 −0.07 −0.05
p 0.81 0.96 0.74 0.68 0.66 0.77 <0.05* 0.16 0.62 0.74
Leptin 57 r 0.16 0.24 −0.09 −0.09 0.00 0.00 0.10 0.05 0.10 0.11
p 0.23 0.07 0.52 0.51 0.99 0.98 0.48 0.73 0.47 0.43
Adiponectin 39 r 0.11 0.03 −0.16 −0.09 0.20 0.09 0.43 0.08 −0.01 −0.03
p 0.52 0.84 0.33 0.57 0.21 0.59 <0.01* 0.62 0.94 0.87

Spearman correlation coefficient is denoted by ‘r’ and ‘p’ refers to p−value for that correlation.

*

p<0.05

**

Significant after adjusting for multiple comparisons, i.e., unadjusted p−value < 0.0008. The significant correlations are highlighted.