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. 2015 Feb 27;16(3):4518–4559. doi: 10.3390/ijms16034518

Figure 1.

Figure 1

Comparative models showing the factors involved in tRNA import in mitochondria from (a) S. cerevisiae, (b) land plants and (c) T. brucei. Black arrows represent characterized steps of import, whereas grey dotted arrows represent tentative steps. OM and IM stand for mt-outer and inner membrane, respectively. TIM and TOM stand for translocase of the inner and outer mt-membrane. The subunits of TOM and TIM complexes are distinguished by their size given in kDa. Hsp describes different heat shock proteins, Eno2p stands for the glycolytic enzyme Enolase, aaRS for aminoacyl-tRNA synthetase, VDAC for the Voltage Dependent Anion Channel, pre-MSK1 for the precursor of the mitochondrial lysyl-tRNA synthetase, eEF1a for the eukaryotic translation elongation factor 1 alpha, and Tb for Trypanosoma brucei. Proteins shown in grey denote proteins belonging to the protein import machinery. Adapted from refs [10,22].