Table 4.
Tear cytokines in microbial keratitis.
| Tear Cytokine | Fungal Keratitis | Gram-Positive Bacterial Keratitis | Gram-Negative Bacterial Keratitis | Contralateral Non-Infected Eye | p Value (Compared with Contralateral Non-Infected Eye) |
|---|---|---|---|---|---|
| IL-1β pg/mL | 1135 ± 764 * | 64 ± 40 | 423 ± 240 * | 58 ± 89 * | <0.05 |
| IL-6 pg/mL | 4172 ± 1873 * | 758 ± 1166 | 1596 ± 971 * | 25 ± 17 * | <0.05 |
| IL-8 pg/mL | >2500 * | >2500 * | >2500 * | 420 ± 377 * | <0.05 |
| IL-10 pg/mL | 43 ± 35 | 34 ± 23 | 107 ± 166 | 13 ± 3 | NS |
| IL-12p70 pg/mL | 12 ± 6 | 12 ± 1 | 4.0 ± 1 | 5 ± 5 | NS |
| TNF-α pg/mL | 28 ± 21 | 8 ± 4 | 8 ± 2 | 14 ± 7 | NS |
NS—Not significant; Results are expressed in pg/mL; Kit detection limits were as follows: IL-8, 3.8 pg/mL; IL-1β, 7.2 pg/mL; IL-6, 2.5 pg/mL; IL-10, 3.3 pg/mL; TNF-α, 3.7 pg/mL; and IL-12p70, 1.9 pg/mL.