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Chemical structure of [68Ga]-DOTATOC (DOTA(0)-Phe(1)-Tyr(3))octreotide). It shows high affinity to SSTR2 (Somatostatin Receptor 2)—a receptor overexpressed in neuroendocrine tumors. The blue portion of the molecule is responsible for the SSTR2 specificity, whereas the radionuclide 68Ga contained in the chelator DOTA (red) acts as the signal source for PET imaging. For reasons of clarity, chelation bonds are omitted.
