Table 2.
Method | Spatial Resolution | Temporal Resolution | Sensitivity [mol/L] | Costs | Advantages | Drawbacks |
---|---|---|---|---|---|---|
CT | 50–200 µm | Minute | – | Low | Generation of anatomical images | It is difficult to generate functional, non-quantitative |
MRI | 25–100 µm | Minute to hour | 10−3–10−5 | Very high | High spatial resolution, non-radioactive tracers | Low sensitivity |
PET | 2–5 mm | Second to minute | 10−11–10−12 | Very high | The most sensitive imaging method, quantitative method, allows to use biologically relevant radionuclides | Imaging of large areas is expensive, low spatial resolution |
SPECT | 7.5–10 mm | Minute | 10−10–10−11 | High | Simultaneous multi-probe imaging is possible | Low spatial resolution |
CT: Computed Tomography; MRI: Magnetic Resonance Imaging; PET: Positron Emission Tomography; SPECT: Single Photon Emission Computed Tomography.