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. 2015 Mar 4;16(3):4918–4946. doi: 10.3390/ijms16034918

Table 2.

Methods used for molecular imaging in oncology [8,184,185].

Method Spatial Resolution Temporal Resolution Sensitivity [mol/L] Costs Advantages Drawbacks
CT 50–200 µm Minute Low Generation of anatomical images It is difficult to generate functional, non-quantitative
MRI 25–100 µm Minute to hour 10−3–10−5 Very high High spatial resolution, non-radioactive tracers Low sensitivity
PET 2–5 mm Second to minute 10−11–10−12 Very high The most sensitive imaging method, quantitative method, allows to use biologically relevant radionuclides Imaging of large areas is expensive, low spatial resolution
SPECT 7.5–10 mm Minute 10−10–10−11 High Simultaneous multi-probe imaging is possible Low spatial resolution

CT: Computed Tomography; MRI: Magnetic Resonance Imaging; PET: Positron Emission Tomography; SPECT: Single Photon Emission Computed Tomography.