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. 2015 Mar 10;16(3):5434–5451. doi: 10.3390/ijms16035434

Figure 4.

Figure 4

Impaired adhesion capacity in blood eosinophils from asthmatic patients after SOCS3 gene silencing. (A) NT and SOCS3 siRNA treated eosinophils were incubated with IL-4, IL-5, IL-13, and PGE2 for 1 or 2 h and then allowed to adhere to fibronectin-coated wells for 30 min. Results are expressed as mean ± SD of adhered cell percentages estimated by residual eosinophils peroxidase (EPO) measurement; and (B) LFA-1, ICAM-1, VLA4, VCAM-1, and Integrin-α2 surface expression on blood eosinophils from seven asthmatic patients incubated with SOCS3 siRNA or NT siRNA were determined by flow cytometry. * p < 0.05 between groups.